Publications by authors named "B Sumathi"
Purpose: The aim is to validate the third generation Thyrotropin receptor antibody (TRAb) assay for predicting neonatal thyroid dysfunction and adverse pregnancy outcomes in pregnant women with Graves' disease.
Methods: This prospective cohort study was conducted in TRAb positive pregnant women with Graves' disease and their off springs. The primary outcome was to assess different forms of neonatal thyroid dysfunction in relation to maternal and neonatal TRAb levels.
Article Synopsis
- Insulin resistance and hyperinsulinemia contribute to polycystic ovary syndrome (PCOS), and the study aimed to compare metformin alone against metformin combined with Myoinositol and d-chiro-inositol in treatment outcomes for PCOS patients.
- Conducted over 6 months, the randomized controlled trial included overweight and obese women aged 18-35 with PCOS, divided into two treatment groups to assess various health parameters.
- Results showed that both treatments improved menstrual cycle regularity, but the myoinositol group had significantly better outcomes in quality of life, while pregnancy rates were similar; other hormonal and metabolic improvements weren't statistically significant.
Solitary Rectal Ulcer Syndrome (SRUS) was a relatively uncommon and easily misdiagnosed clinical entity in children. The diagnosis of this condition was often delayed due to lack of clinical suspicion. Only case series were available and no definitive treatment was postulated.
View Article and Find Full Text PDFPancreatic disease in children has a wide clinical spectrum and may present as Acute pancreatitis (AP), Acute recurrent pancreatitis (ARP), Chronic pancreatitis (CP) and Pancreatic disease without pancreatitis. This article highlights the etiopathogenesis and management of pancreatitis in children along with clinical data from five tertiary care hospitals in south India [Chennai (3), Cochin and Pune].
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