The clinical role of micrometastatic disease in sentinel lymph nodes in breast cancer.

Purpose: Complete axillary lymph node dissection (cALND) is the standard procedure in treating the patients with tumor-positive sentinel nodes (SLNs). However, approximately half of these patients have not additional metastases in their axilla and therefore do not benefit from cALND. Our aim was to examine the outcome of patients with tumor-positive SLNs without cALND.

[Value of cytologic diagnosis in rapid intraoperative diagnosis of mediastinal lymphadenopathy and tumors of the lung and mediastinum].

Extemporary (EXT) analysis is unavoidable in establishing the tumor diagnosis, operability and the extent of the operation. Alternative approach is cytologic analisis which, because of its simple methodology, provides results even faster. In this paper, the results of cytologic imprints (CI) and EXT finding were compared with definite histopathologic diagnosis (HDP) to determine the value of both methods.

AdoP assay detection of mycoplasmal contamination in biological media.

The AdoP assay has been shown to be reliable in controlling the absence of mycoplasmas in filtered sera. We therefore compared its effectiveness with that of other tests in the detection of animal cell contamination by mycoplasmas.

Assay for detection of adenosine phosphorylase from mycoplasmas.

A microtechnique is described which permits simple evaluation of the activity of the enzyme adenosine phosphorylase (AdoP), present in all mycoplasmas tested thus far. The good solubility and stability of AdoP and the sensitivity of the assay should be advantageous in detecting mycoplasmas in biological samples such as animal sera, cell cultures and vaccines.