Publications by authors named "B Stetson"
Background: More than 1 million women have their labor induced in the United States each year, and synthetic oxytocin infusion is the most common method used. However, compared to spontaneous labor, medical induction is resource intensive, has increased obstetric risks, and is associated with less successful breastfeeding. In contrast to the endogenous oxytocin hormone, which is released in a pulsatile fashion in the brain, synthetic oxytocin is continuously infused intravenously, resulting in important limitations related to efficacy, safety, and cost.
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- The study aimed to investigate the effects of exceeding a 20 milliunits/min rate of oxytocin during labor augmentation, despite hospital guidelines suggesting a maximum limit without clear safety evidence.
- A secondary analysis was conducted on a trial of pregnant women, comparing outcomes for those who exceeded this rate to those who did not, focusing on cesarean deliveries and other labor outcomes.
- Results indicated that while 19.9% of participants exceeded the 20 milliunits/min threshold, there was no significant increase in adverse outcomes like cesarean delivery or infection linked to higher oxytocin doses, although older participants had a higher likelihood of exceeding this dose.
Importance: Fetal ultrasonography is essential for confirmation of gestational age (GA), and accurate GA assessment is important for providing appropriate care throughout pregnancy and for identifying complications, including fetal growth disorders. Derivation of GA from manual fetal biometry measurements (ie, head, abdomen, and femur) is operator dependent and time-consuming.
Objective: To develop artificial intelligence (AI) models to estimate GA with higher accuracy and reliability, leveraging standard biometry images and fly-to ultrasonography videos.
Article Synopsis
- Iron deficiency (ID) in infants can lead to serious long-term cognitive issues, but currently, iron status is not routinely tested at birth, making the extent of the problem unclear in the U.S.! -
- A study compared iron levels in cord blood from twins (54 samples) and singletons (24 samples) and found that 21% of twins and 20% of singletons were iron deficient based on serum ferritin levels! -
- Factors like gestational age, maternal race, and infant sex affected iron levels, and while 40% of mothers were anemic, this did not correlate with their babies' iron status, indicating a need for further research on at-risk pregnancies!