Publications by authors named "B Steffan"
Article Synopsis
- The study explored how human vocal fold fibroblasts (hVFF) interact with macrophages in the presence of cigarette smoke extract (CSE) and vibration, focusing on vocal fold inflammation.
- Researchers cultured hVFF with CSE, applying either static or dynamic conditions, and then measured various mRNA and protein levels to assess inflammation.
- Findings revealed that vibration may reduce CSE-induced inflammatory responses in hVFF, suggesting potential mechanisms to address voice disorders linked to smoking-related inflammation.
This investigation explores the complex interplay between menopause and neurodivergence in the workplace, employing thematic analysis of qualitative data from 43 participants across the United Kingdom and the United States. Findings reveal that menopause transitions intensify symptoms of neurodivergence, and can interrupt how women engage with paid work. By shining a light on these under-reported experiences at work, we demonstrate how employers can better support their neurodivergent employees during menopause.
View Article and Find Full Text PDFArticle Synopsis
- - The review highlights how eosinophils and airway epithelial cells interact in asthma, showing that eosinophils can influence epithelial cell functions and vice versa.
- - It discusses the impact of eosinophil products, like granule proteins, on airway cells and the various mediators released by epithelial cells that affect eosinophil behavior.
- - The key takeaway is that these interactions can produce both harmful and helpful effects in the context of asthma, pointing to a complex signaling relationship between these cell types.
Objectives: The isolated or combined effects of vibration and smoke extract (SE) from the IQOS™ "heat-not-burn" technology on human vocal fold fibroblasts (hVFF) were evaluated in an in vitro setting in order to elucidate their influence on vocal fold (patho-) physiology.
Study Design: Experimental pilot study using intervention with IQOS™-SE in vitro.
Methods: Immortalized hVFF were exposed to IQOS™-SE or control medium under static or vibrational conditions.
Article Synopsis
- Filamentous fungi have many natural products that are hard to study in labs, but scientists found a way to isolate new ones using special genetic techniques.
- They changed how fungi produce certain chemicals, leading to higher amounts of new compounds but less of a well-known one called austinol.
- By removing a specific gene, they were able to bring back the original chemical balance, giving new clues about how fungi create different substances.