Publications by authors named "B Stankiewicz"
Background: Lidocaine, a widely used local anaesthetic, also serves as an adjuvant in pain management. However, its use in children is off-label. This study aimed to determine if intravenous lidocaine alleviates the haemodynamic, metabolic, and hormonal responses to intubation and laparoscopic surgery in children.
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- The study investigates how remote ischemic preconditioning (RIPC) affects tryptophan (TRP) and its metabolites (kynurenines) in semi-professional long-distance runners after intense exercise.
- A total of 27 runners were divided into a RIPC group and a placebo (SHAM) group, with blood samples taken at various times to analyze changes in TRP and kynurenines post-exercise.
- Results showed that the RIPC group had lower levels of certain kynurenines and a higher decrease in TRP after exercise, suggesting RIPC could influence brain health, though more research is necessary.
Exercise-induced inflammation can influence iron metabolism. Conversely, the effects of vitamin D, which possesses anti-inflammatory properties, on ultramarathon-induced heart damage and changes in iron metabolism have not been investigated. Thirty-five healthy long-distance semi-amateur runners were divided into two groups: one group received 150,000 IU of vitamin D 24 h prior to a race ( = 16), while the other group received a placebo ( = 19).
View Article and Find Full Text PDFUbiquinone (Coenzyme Q-10) Supplementation Influences Exercise-Induced Changes in Serum 25(OH)D and the Methyl-Arginine Metabolites: A Double-Blind Randomized Controlled Trial.
Antioxidants (Basel)
June 2024
Article Synopsis
- - Researchers investigated how exercise affects serum methyl-arginine and vitamin D levels, noting a gap in studies on the combined effects with antioxidants, particularly coenzyme Q (CoQ).
- - In a study with 28 healthy men, participants exercised to exhaustion and were divided into a CoQ supplementation group and a control group, with blood samples taken before and after the exercise sessions.
- - Results showed that CoQ supplementation significantly increased serum CoQ levels, altered vitamin D and methyl-arginine metabolism post-exercise, and suggested potential benefits for athletic performance and recovery.
Article Synopsis
- * Two models of a small molecule, one rigid and one flexible, are used to test the assumptions that internal and rotational motions are decoupled and that the molecule is rigid.
- * The findings suggest that the rigid model can reproduce the target RDC values, but struggles with orientation distribution, while the flexible model fails to reproduce both target RDC values and orientation distribution, highlighting challenges in studying flexible biomolecules.