Bullying of LGBTQ+ children and adolescents in schools: understanding the phenomenon, consequences, and international standards with a focus on the polish context.

Bullying refers to repetitive, aggressive behavior intended to harm or intimidate others. Cyberbullying extends this aggression to digital platforms, involving harassment via social media, texts, or emails. These forms of bullying are particularly damaging to LGBTQ+ youth, who often face discrimination based on their sexual orientation or gender identity.

Blunted Cortisol Awakening Response Is Associated with External Attribution Bias Among Individuals with Personality Disorders.

Background/objectives: The dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been associated with various mental disorders. One of the most commonly described parameters of HPA axis functioning is the cortisol awakening response (CAR). To date, few studies have been conducted on the relationship between personality disorders and CAR.

Fractional flow reserve versus angiography-guided revascularization in coronary artery disease. Systematic review and meta-analysis.

Background: Randomized controlled trials (RCTs) comparing the clinical outcomes of fractional flow reserve (FFR)-guided and angiography-guided revascularization in patients with coronary artery disease yielded inconsistent results.

Aims: This study aimed to assess whether FFR-guided revascularization reduces the rates of hard clinical endpoints in comparison with the angiography-guided approach alone.

Methods: This systematic review was conducted in June 2024 using Embase, Clinicaltrials.

Cystatins: unravelling the biological implications for neuroprotection.

Cystatins, a family of proteins known for their inhibitory role against cysteine proteases, have garnered significant attention in the field of neurodegeneration. Numerous genetic, experimental, and clinical studies concerning cystatin C suggest it plays an important role in the course of neurodegenerative diseases. Its beneficial effects are associated with cysteine protease inhibition, impact on β-amyloid aggregation, as well as regulation of cell proliferation, autophagy, and apoptosis.

The Impact of Rationing Nursing Care on Patient Safety: A Systematic Review.

BACKGROUND Rationing of nursing care (RONC) has been associated with poor patient outcomes and is a growing concern in healthcare. The aim of this systematic study was to investigate the connection between patient safety and the RONC. MATERIAL AND METHODS A thorough search of electronic databases was done to find research that examined the relationship between restricting nurse services and patient safety.