Publications by authors named "B Spurny-Dworak"
Morphological correlates of anxiety-related experiences during a ketamine infusion.
World J Biol Psychiatry
November 2024
Article Synopsis
- * In a study with 17 healthy volunteers, the relationship between anxiety during ketamine infusion and brain structure was explored, revealing that smaller hippocampal volumes were associated with higher anxiety scores.
- * The findings indicate that the size of hippocampal subfields could help predict anxiety experiences during ketamine treatment and may also influence treatment outcomes in future therapies.
MAO-A catalyzes the oxidative degradation of monoamines and is thus implicated in sex-specific neuroplastic processes that influence gray matter (GM) density (GMD) and microstructure (GMM). Given the exact monitoring of plasma hormone levels and sex steroid intake, transgender individuals undergoing gender-affirming hormone therapy (GHT) represent a valuable cohort to potentially investigate sex steroid-induced changes of GM and concomitant MAO-A density. Here, we investigated the effects of GHT over a median time period of 4.
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- COVID-19 restrictions had a significant impact on mental health, with concerns that these measures could worsen psychiatric symptoms in the population.
- A study used structural MRI, serum analyses, and psychometric assessments to explore changes in brain neurobiology and mental health symptoms in patients with recurrent major depressive disorder and healthy individuals during the pandemic.
- Findings indicated no significant changes over time in brain structure or depressive symptoms, suggesting that nine months of lockdown measures did not visibly affect brain morphology or mental health outcomes in the studied group.
Self-reported sexual orientation of transgender individuals occasionally changes over transition. Using functional magnetic resonance imaging, we tested the hypothesis that neural and behavioral patterns of sexual arousal in transgender individuals would shift from the assigned to the experienced gender (e.g.
View Article and Find Full Text PDFBackground: Among its pleiotropic properties, gender-affirming hormone therapy (GHT) affects regional brain volumes. The hypothalamus, which regulates neuroendocrine function and associated emotional and cognitive processes, is an intuitive target for probing GHT effects. We sought to assess changes to hypothalamus and hypothalamic subunit volumes after GHT, thereby honouring the region's anatomical and functional heterogeneity.
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