Immune checkpoint inhibitors: Utilizing patient's own immunity to treat oral cancer.

Head and Neck squamous cell carcinoma is an immunosuppressive state. HNSCC evades immune responses through multiple resistance mechanisms. Because of better understanding of interaction between tumour microenvironment and immune regulators, there is increasing interest in role of immunotherapy as a treatment modality of HNSCC.

COVID-19 status and utilisation of essential maternal and child healthcare services during the pandemic in Ahmedabad, India.

Background: Access to essential healthcare services is pertinent to the achievement of universal health coverage in any nation. The COVID-19 lockdown was used to mitigate the spread of the pandemic. Consequently, there was a reduction in the Utilisation of Basic Healthcare Services (UBHS) in diverse dimensions.

Towards molecular structure discovery from cryo-ET density volumes via modelling auxiliary semantic prototypes.

Cryo-electron tomography (cryo-ET) is confronted with the intricate task of unveiling novel structures. General class discovery (GCD) seeks to identify new classes by learning a model that can pseudo-label unannotated (novel) instances solely using supervision from labeled (base) classes. While 2D GCD for image data has made strides, its 3D counterpart remains unexplored.

Intersectoral collaboration and health system resilience during COVID-19: learnings from Ahmedabad, India.

Health system resilience refers to the capacity of a health system to effectively anticipate, assimilate, adjust to and recuperate from unforeseen disruptions and pressures. Evidence indicates that low- and middle-income countries (LMICs) have a double burden of dealing with the existing shortage of health resources in managing both non-emergency care and emergency care during epidemics. Intersectoral collaboration plays a pivotal role in managing crises such as pandemics.