Publications by authors named "B Siva"

Global agricultural production is significantly hampered by insect pests, and the demand for natural pragmatic pesticides with environmental concern remains unfulfilled. Ageratina adenophora (Spreng.) also known as Crofton weed, is an invasive perennial herbaceous plant that is known to possess multiple bioactive compounds.

View Article and Find Full Text PDF

Three new spatane diterpenoids (1-3) were isolated from the brown alga Stoechospermum marginatum together with three known compounds (4-6). The structures of these compounds were determined by the detailed NMR spectroscopic and Mass spectrometric analyses. All the isolated compounds were screened for their cytotoxic potentials against a panel of four human cancer cell lines, which include DU145 (Prostate), B16F10 (Melanoma), MDA MB-231 (Breast), and HeLa (Cervical) along with a normal cell line (HEK).

View Article and Find Full Text PDF
Article Synopsis
  • * For a long time, there were no approved medications for treating NASH, but recent FDA approval of a drug called Rezdiffra (Resmetirom) may provide new treatment options, while lifestyle changes remain crucial for managing the disease.
  • * The review discusses how NASH affects liver drug metabolism and transport due to changes in certain liver transporters and enzymes, highlighting the significance of understanding these interactions for better treatment approaches.
View Article and Find Full Text PDF

Traditional medicinal plants have been used for centuries for their immunomodulatory properties and therapeutic potentials. The present study aims to investigate the immunomodulatory constituents from traditional medicinal plant, Tinospora cordifolia (willd.).

View Article and Find Full Text PDF

The present study was intended for the identification of secondary metabolites in acetone extract of the lichen using UPLC-ESI-QToF-MS/MS and the detection of bioactive compounds. This study led to the identification of 22 metabolites based on their MS/MS spectra, accurate molecular masses, molecular formula from a comparison of the literature database (DNP), and fragmentation patterns. In addition, potent antioxidant and α-glucosidase inhibitory potentials of acetone extract of motivated us to isolate 10 metabolites, which were characterized as salazinic acid (), norlobaridone (), atranorin (), lecanoric acid (), lichesterinic acid (), protolichesterinic acid (), methyl hematommate (), iso-rhizonic acid (), atranol (), and methylatratate ( based on their spectral data.

View Article and Find Full Text PDF