Ensembl 2025.

Ensembl (www.ensembl.org) is an open platform integrating publicly available genomics data across the tree of life with a focus on eukaryotic species related to human health, agriculture and biodiversity.

Environmental impact assessment based on particulate matter, and chlorophyll content of urban trees.

The amount of dust deposited on tree leaves is a cost-effective indicator of air quality. Our aim was to explore the leaf surface deposition, and chlorophyll content of leaves along a road section that started at an intersection, and ended in a less disturbed suburban area in Debrecen, Hungary. We also assessed the impact of meteorological conditions on the amount of deposited dust.

Comparative Study of TPGS and Soluplus Polymeric Micelles Embedded in Poloxamer 407 In Situ Gels for Intranasal Administration.

This study aims to highlight the importance of choosing the appropriate co-polymer or co-polymer mixed combinations in order to design value-added nasal dosage forms. Local therapy of upper respiratory tract-related infections, such as nasal rhinosinusitis is of paramount importance, thus advanced local therapeutic options are required. Dexamethasone was encapsulated into three different polymeric micelle formulations: Soluplus or TPGS-only and their mixed combinations.

A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine.

Current treatment outcome of patients with glioblastoma (GBM) remains poor. Following standard therapy, recurrence is universal with limited survival. Tumors from 173 GBM patients are analysed for somatic mutations to generate a personalized peptide vaccine targeting tumor-specific neoantigens.

Association between affective temperaments and the severity and the extent of coronary artery disease as obtained by coronary CT angiography.

Background: Affective temperaments are documented predictors of psychopathology, but cumulating data suggest their relationship with coronary artery disease (CAD). We aimed to evaluate their role in relation to surrogate semiquantitative markers of coronary plaque burden, as assessed by coronary CT angiography (CCTA).

Methods: We included 351 patients who were referred for CCTA due to suspected CAD.