Publications by authors named "B Shpitz"
Background: Pseudomonas aeruginosa (P. aeruginosa), Escherichia coli (E. coli), and Staphylococcus aureus (S.
View Article and Find Full Text PDFBackground: Anastomotic leak is regarded as one of the most feared complications of bowel surgery; avoiding leaks is a major priority. Attempts to reduce or eliminate leaks have included alternate anastomotic techniques. Human oral mucosa stem cells (hOMSC) are self-renewing and expandable cells derived from buccal mucosa.
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- Following an intestinal anastomotic leak, creating a stoma is often seen as the safest option, but it can lead to complications and a T drain may provide a less invasive alternative when appropriate.
- A study analyzed 41 cases of anastomotic leaks, where 12 patients were treated with a T drain, achieving a high success rate of 92% in full recovery, indicating its effectiveness.
- The research emphasizes that a T drain approach is beneficial in specific situations where the leak is contained, the rest of the anastomosis is stable, and the condition of the abdomen allows for it, potentially avoiding the need for a stoma.
Background And Objectives: Surgical trauma in patients undergoing colorectal cancer resection generates local and systemic inflammatory responses that can affect oncological outcomes. Post-operative peritoneal fluids of patients undergoing colorectal surgery increase the pro-malignant effect of cancer cells in vitro with correlation to elevated TNFα in these fluids. This study evaluated whether inhibiting TNFα in patients' postoperative fluid biopsies would attenuate this effect.
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