Precision medicine in practice: unravelling the prevalence and antibiograms of urine cultures for informed decision making in federal tertiary care- a guide to empirical antibiotics therapy.

Background And Objectives: Urinary tract infections (UTIs), one of the most prevalent bacterial infections, are facing limited treatment options due to escalating concern of antibiotic resistance. Urine cultures significantly help in identification of etiological agents responsible for these infections. Assessment of antibiotic susceptibility patterns of these bacteria aids in tackling the emerging concern of antibiotic resistance and establishment of empirical therapy guidelines.

Lact-Pred: A Predictor Developed for Identification of Beta-Lactamases Using Statistical Moments and PseAAC via 5-Step Rule.

Beta-lactamase (-lactamase) produced by different bacteria confers resistance against -lactam-containing drugs. The gene encoding -lactamase is plasmid-borne and can easily be transferred from one bacterium to another during conjugation. By such transformations, the recipient also acquires resistance against the drugs of the -lactam family.

Intelligent Cardiovascular Disease Prediction Empowered with Gradient Descent Optimization.

Disorders of the heart and blood vessels are named cardiovascular disease. 'The heart's proper functionality is of an utmost necessity for the survival of life. The death rate due to heart disease, has been increased rapidly.

Correction of faulty sensors in phased array radars using symmetrical sensor failure technique and cultural algorithm with differential evolution.

Three issues regarding sensor failure at any position in the antenna array are discussed. We assume that sensor position is known. The issues include raise in sidelobe levels, displacement of nulls from their original positions, and diminishing of null depth.

Human papillomaviruses (HPV) are associated with multiple myeloma.

Human papillomaviruses (HPV) are small DNA tumor viruses, and are associated with epithelial neoplasias. Although HPV are believed to be exclusively permissive in terminally differentiated squamous cells, we have previously identified HPV sequences in lymphoid tissues of five patients. Because this result suggested that the range of the host virus cells could include cells of lymphoid origin, we used PCR and in situ hybridization to analyze nonepithelial tissues of patients with multiple myeloma from two institutions.