Publications by authors named "B Sharifkashani"
Behçet's disease (BD) is a multisystem, progressive, and inflammatory disorder of unknown etiology. Vasculitis is believed to underlie various clinical manifestations of BD and is known to be one of the main causes of death due to BD, in cases of large vessel involvement. The current study is done in order to examine the effects of rituximab on the patient's debilitating clinical manifestations, as a result of not responding to the standard treatment regimens.
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- The INSPIRATION-S trial investigated the effects of atorvastatin versus placebo on 90-day outcomes in ICU patients with COVID-19, focusing on complications like thrombosis and mortality.
- Results showed that atorvastatin users had a slightly lower incidence of severe outcomes compared to placebo (33.1% vs 38.0%), but the difference was not statistically significant.
- The study indicated a potential benefit of atorvastatin, particularly for patients who began treatment within the first week of symptom onset, with improved functional status noted, although definitive conclusions couldn't be made.
Donor heart selection: Evidence-based guidelines for providers.
J Heart Lung Transplant
January 2023
The proposed donor heart selection guidelines provide evidence-based and expert-consensus recommendations for the selection of donor hearts following brain death. These recommendations were compiled by an international panel of experts based on an extensive literature review.
View Article and Find Full Text PDFBackground: Pulmonary artery pressure (PAP) is one of the most important and valuable markers in cardiovascular disease, measured by right heart catheterization (RHC) as the gold standard diagnostic modality. However, due to several limitations, such as invasiveness, lack of repeatability, and high health costs, echocardiographic estimation of PAP has been used to substitute RHC for diagnosis and monitoring of this disease. This study aimed to evaluate the correlation of echocardiographic and RHC estimations of systolic PAP.
View Article and Find Full Text PDFPulmonary artery hypertension (PAH) occurs when mean pulmonary artery pressure (PAP) is higher than 25 mmHg in rest or 30 mmHg during activity. Idiopathic pulmonary artery hypertension (IPAH) is defined as PAH without a definite reason. The IPAH is a rare disease with a high mortality rate if left untreated.
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