Publications by authors named "B Seyoum"
Background: Clinically diagnosed pulmonary tuberculosis (TB) (CDPTB) patients account for a huge proportion of TB. However, little is known about the genetic diversity and drug resistance profile of Complex (MTBC) strains in this group of patients.
Method: Unmatched case-control study was conducted among 313 PTB patients to compare the genetic diversity of MTBC and their drug resistance profiles among CDPTB ( = 173) and bacteriologically confirmed pulmonary TB (BCPTB) ( = 140) patients.
Introduction: An electronic medical record (EMR) can enhance the quality of care and patient outcomes. Ethiopia started the implementation of EMR in 2013. However, its adoption among healthcare providers has been low.
View Article and Find Full Text PDFAntipsychotics are associated with severe metabolic side effects including insulin resistance; however, the mechanisms underlying this side effect are not fully understood. The skeletal muscle plays a critical role in insulin-stimulated glucose uptake, and changes in skeletal muscle DNA methylation by antipsychotics may play a role in the development of insulin resistance. A double-blind, placebo-controlled trial of olanzapine was performed in healthy volunteers.
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- Acinetobacter baumannii is an opportunistic pathogen responsible for various infections, particularly in surgical sites, and this study focused on characterizing strains that produce extended-spectrum beta-lactamases (ESBL) and are resistant to carbapenems.
- A multicenter study in Ethiopia identified a variety of Acinetobacter species using advanced microbiological techniques, revealing high rates of ESBL and carbapenem resistance among isolates from surgical site infections.
- Results indicated that 93% of isolates produced ESBL enzymes, with higher prevalence of resistance genes found through whole genome sequencing, emphasizing significant public health concerns regarding antibiotic resistance in Acinetobacter species across different hospitals.
The World Health Organization [WHO] recommends a genotype-specific human papillomavirus [HPV] vaccination as a primary prevention strategy to control the burden of cervical cancer globally. In Ethiopia, where the non-vaccine-targeted HPV genotypes have not been adequately studied, a vaccination initiative was launched in 2018 targeting HPV-6,-11, -16, and -18 for girls aged 14-18 years. The co-existence of both vaccine-targeted and non-targeted genotypes is a serious concern, as it can accelerate cancer progression.
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