Publications by authors named "B Seese"

Introduction: Pirfenidone was the first anti-fibrotic drug approved in Europe in 2011 for the treatment of mild-to-moderate idiopathic pulmonary fibrosis.

Objectives: To investigate the clinical course of mild-to-moderate idiopathic pulmonary fibrosis in pirfenidone-treated patients in a real-world setting.

Methods: The non-interventional study was conducted at 18 sites in Germany from 6/2014-12/2016.

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Article Synopsis
  • Tuberculosis (TB) remains a significant global health issue, with misdiagnosis contributing to its high mortality rate, highlighting the need for better diagnostic tests.
  • A new molecular test called T-Track TB was evaluated and shown to have a sensitivity of 94.9% and specificity of 93.8%, outperforming the existing QuantiFERON-TB Gold Plus test which had a sensitivity of 84.3%.
  • The T-Track TB test demonstrated reliable performance, correctly classifying the majority of active TB cases compared to non-TB controls, indicating its potential as a superior diagnostic tool for TB.
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Background:  The number of invasive and non-invasive long-term out-of-hospital ventilations has been increasing rapidly for years. At the same time, there is poor information on the quality of care of out-of-hospital ventilated patients. The present investigation was conducted as part of the OVER-BEAS study.

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Background:  The number of invasive and non-invasive long-term out-of-hospital ventilations has been increasing rapidly for years. At the same time, there is poor information on the quality of care of out-of-hospital ventilated patients. The present investigation was conducted as part of the OVER-BEAS study.

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Mycobacteriophages Cambiare, FlagStaff, and MOOREtheMARYer are newly isolated phages of Mycobacterium smegmatis mc(2) 155 recovered from soil samples in Pittsburgh, PA. All three genomes are closely related to cluster G mycobacteriophages but differ sufficiently in nucleotide sequence and gene content to warrant division of cluster G into several subclusters.

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