Publications by authors named "B Sarkari"
Article Synopsis
- Human cytomegalovirus (HCMV) can cause severe health issues, especially in those with weakened immune systems, and current diagnostic tests for HCMV have limitations in sensitivity and specificity.
- Researchers aimed to create a new, more accurate multi-epitope antigen for diagnosing HCMV infections using immunoinformatic methods, selecting five key proteins based on their antigenic properties.
- The designed antigen showed promising stability and antigenicity without cross-reactivity and is a potential candidate for better HCMV diagnosis, although further lab testing is needed to confirm its effectiveness.*
Background: The sensitivity of parasitological and molecular methods is unsatisfactory for the diagnosis of strongyloidiasis, and serological techniques are remaining as the most effective diagnostic approach. The present study aimed to design and produce a chimeric recombinant antigen from Strongyloides stercoralis immunoreactive antigen (SsIR) and Ss1a antigens, using immune-informatics approaches, and evaluated its diagnostic performance in an ELISA system for the diagnosis of human strongyloidiasis.
Methodology/principal Findings: The coding sequences for SsIR and Ss1a were selected from GenBank and were gene-optimized.
Background: is one of the most important causes of animal toxocariasis with global distribution. We aimed to find out the seroprevalence of toxocariasis in dogs in a rural area in Fars Province, south of Iran.
Methods: Dogs blood samples were collected from 60 dogs in three rural areas in the Sar Mashhad region, Fars Province.
Infection in Synanthropic Rodents: Evidence for the Urbanization of Zoonotic Cutaneous Leishmaniasis (ZCL) in Southern Iran.
Can J Infect Dis Med Microbiol
March 2024
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to investigate the infection of rodents with in an urban area of Fars Province, located in southern Iran. Rodents were trapped and samples from the liver, spleen, and skin were collected.
View Article and Find Full Text PDFBackground: Inflammation and oxidative activities within the gut play major roles in the pathogenesis of ulcerative colitis (UC). We aimed to determine the effect of , an antioxidant and anti-inflammatory agent, on the colon histological characteristics in acetic acid (AA)-induced UC in rat models.
Methods: Thirty-six male rats with AA-induced colitis were divided into 5 groups: no treatment (AA); daily treatment with 300 mg/kg orally (MO) and rectally (MR); and 100 mg/kg mesalamine orally (AO) and rectally (AR).