Publications by authors named "B Sanggetha Lakshmi"

Article Synopsis
  • Multi-targeted therapies are increasingly recognized for their effectiveness in treating complex diseases such as Type 2 diabetes and obesity, utilizing multiple mechanisms to enhance benefits while minimizing side effects.
  • The study investigates the potential of Cocculus hirsutus methanol extract (CME) and its hydromethanolic fraction (HMF), revealing significant inhibition of key enzymes related to glucose metabolism and insulin signaling, which indicates their potential in improving metabolic health.
  • HMF was particularly effective, showing improved glucose uptake, increased insulin sensitivity through GLUT4 expression, and reduced lipid accumulation by inhibiting adipogenesis regulators, marking its promise as a therapeutic option.
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Recurrent pregnancy loss (RPL) is defined as the spontaneous loss of two or more pregnancies before reaching viability. Diagnosis for couples with RPL usually involves only the female partner. However, it is seen that male partners contribute equally to the occurrence of spontaneous abortions as the Y chromosome harbors several genes that control spermatogenesis and the quality of sperms.

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One of the primary concerns in the field of green synthesis of nanoparticles (NPs) utilizing plant materials is the scarcity of high purity, challenges in achieving large-scale production, and limited global accessibility. Hygienic preparation and safe storage of plant extracts are also considerable challenges in this field. So, an investigation was started to overcome these limitations.

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Toxic intermediates in food caused by chloramphenicol (CP) and furazolidone (FZ) have gained interest in research toward their detection. Hence, fast, reliable, and accurate detection of CP and FZ in food products is of utmost importance. Here, a novel molybdenum disulfide-connected carbon nanotube aerogel/poly (3,4-ethylenedioxythiophene) [MoS/CNTs aerogel/PEDOT] nanocomposite materials are constructed and deposited on the pretreated carbon paste electrode (PCPE) by a facile eletropolymerization method.

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