Publications by authors named "B Sandya Rani"
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View Article and Find Full Text PDFA fluorometric sensor for Tin(II) detection using Azomethine-Triazole organosilane: Turn-off mechanism, antioxidant activity and molecular docking insights.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
The need for metal ion sensors is increasing daily due to the harmful impact of metal ions on human health, the environment, and the aquatic ecosystem. The present study highlights synthesizing an azomethine functionalized triazole allied organosilane (5a) probe as a turn-off fluorometric sensor for Sn(II) recognition with high anti-interference even when the other metal ions are present. The probe (5a) offers a detection limit of up to 6.
View Article and Find Full Text PDFPerception of Social Support and Prevalence of Self-Reported Depressive Symptoms among Patients with Head-and-Neck Squamous Cell Carcinoma Treated at a Tertiary Cancer Centre in North India.
Indian J Palliat Care
October 2024
Objectives: This study was conducted to determine and correlate the perception of social support and the prevalence of self-reported depressive symptoms among patients with head-and-neck squamous cell carcinoma (HNSCC).
Materials And Methods: This cross-sectional study included 100 patients with HNSCC receiving treatment at a tertiary cancer centre in north India. They were enrolled by a convenient sampling technique.
This study introduces a novel multitargeting strategy that combines carbonic anhydrase (CA) activators and cholinesterase (ChE) inhibitors to enhance cognitive functions. A series of tacrine-based derivatives with amine/amino acid moieties were synthesized and evaluated for their dual activity on brain CA isoforms and ChEs (AChE and BChE). Several derivatives, notably compounds , , , and , demonstrated potent CA activation, particularly of hCA II and VII, and strong ChE inhibition with subnanomolar to low nanomolar IC values.
View Article and Find Full Text PDFArticle Synopsis
- Dengue is a mosquito-borne virus that significantly impacts public health in tropical and subtropical areas, and this study examines its effects on pregnancy outcomes.
- A systematic review included 20 studies to analyze the relationship between maternal dengue infection and adverse birth outcomes like preterm birth, low birth weight, small for gestational age, stillbirth, and postpartum hemorrhage.
- The findings showed a higher prevalence of preterm birth (18.3%) and low birth weight (17.1%) among affected pregnancies, though these were not statistically significant, while stillbirth demonstrated a noteworthy correlation in certain studies, indicating a need for more research on this topic.