Publications by authors named "B Sanchez-Sanchez"
Comparison of baseline clinical characteristics among people with type 2 diabetes on second-line therapy previously added with dapagliflozin or another oral glucose-lowering drug: AGORA study.
Clin Investig Arterioscler
June 2024
Introduction: Type 2 diabetes mellitus (T2D) has acquired epidemic proportions worldwide. In recent years, new oral glucose-lowering drugs (OGLD) have emerged that improve the cardiovascular-kidney-metabolic control in T2D people.
Objectives: To compare the baseline clinical-biological characteristics among T2D people to whom had added-on dapagliflozin (DAPA group) or another OGLD (SOC group) second-line hypoglycaemic therapies among the AGORA study population.
Objectives: To determine the prevalence of suspected abuse of non-institutionalised elderly people and the associated variables.
Patients And Method: Observational, descriptive, cross-sectional, multicentre study in patients aged 65 years or older, non-institutionalised, consecutively selected in primary care (PC). The EASI questionnaires (Suspected Elderly Abuse Index), the EAI questionnaire (Suspected Abuse Index in patients with cognitive impairment), the Barthel index, and the EUROQOL-5D questionnaire were used with patients, and the CASE questionnaire and the Zarit test were used with caregivers.
Background: Obstructive sleep apnea (OSA) is associated with multiple comorbidities, including diabetes. Its development is preceded by alterations in the initial phase of carbohydrate metabolism characterized by insulin resistance. This study aims to evaluate the role of intermittent hypoxia and sleep fragmentation characteristic of OSA on the risk of insulin resistance among apneic patients without diabetes.
View Article and Find Full Text PDFBackground: The Female Sexual Function Index (FSFI) is a widely recognized tool for assessing sexual dysfunction (SD). However, its validation for Spanish women suffering from multiple sclerosis (MS) has not yet been conducted.
Aim: The study aimed to examine the psychometric properties of the 19-item Spanish version of the FSFI (svFSFI) in women with relapsing MS.
Article Synopsis
- - The study identifies that insulin and TGF-β signaling pathways work together through a protein called short gastrulation (sog) to influence the remodeling of the extracellular matrix (ECM) in fat tissue of healthy animals.
- - In animals with tumors, sog also affects TGF-β signaling, leading to increased ECM accumulation in the fat body, which negatively impacts muscle health by depleting essential ECM proteins.
- - The research suggests that enhancing insulin signaling, blocking TGF-β signaling, or adjusting ECM levels through certain proteins can help counteract the muscle wasting seen in cancer patients, emphasizing the role of adipose ECM remodeling in cancer cachexia.