Pricing schemes of simultaneous optimization of congestion and air pollution: a case study in Iran.

The problem of traffic congestion and the environmental issues related to air pollution are among the essential problems of urban management that metropolitan cities are trying to mitigate. Given that the contribution of motor vehicles to air pollution is significant, both goals are achieved by managing urban transport. Among the various methods of travel demand management, congestion pricing is a very efficient measure.

Crocin Inhibits the Fibrillation of Human α-synuclein and Disassembles Mature Fibrils: Experimental Findings and Mechanistic Insights from Molecular Dynamics Simulation.

The aggregation of human alpha-synuclein (hαS) is pivotally implicated in the development of most types of synucleinopathies. Molecules that can inhibit or reverse the aggregation process of amyloidogenic proteins have potential therapeutic value. The anti-aggregating activity of multiple carotenoid compounds has been reported over the past decades against a growing list of amyloidogenic polypeptides.

Estimation of economic costs of air pollution caused by motor vehicles in Iran (Isfahan).

Since mobile sources are one of the most important sources of air pollution, this paper tries to estimate the health effects and economic burden due to fine particulate matter (PM) concentrations from motor vehicles. In this regard, we calculate the economic costs of air pollution emitted by vehicles in Isfahan over the period from March 2018 to March 2020. The concentration of urban traffic pollution based on the generalized additive model (GAM) as well as spatial distribution of pollution is estimated.

An efficient method for recombinant production of human alpha synuclein in using thioredoxin as a fusion partner.

Herein, we describe a simple and efficient approach to produce recombinant human α-synuclein (hAS) with high purity from (). The cDNA for hAS was inserted into plasmid pET32a and expressed in BL21 (DE3) with an N-terminal tag containing thioredoxin (trx), followed by a histidine hexapeptide, and a tobacco etch virus (TEV) protease cleavage site (trx-6His-TEV). The fusion protein, trx-hAS, was initially released by osmotic shock treatment from the host cells and subsequently purified using a nickel affinity chromatography.

Non-modifiable Factors of Coronary Artery Stenosis in Late Onset Patients with Coronary Artery Disease in Southern Iranian Population.

Introduction: Coronary Artery disease (CAD) is influenced by genetic factors, environment and culture behavior. The aim of the present study was to evaluate some non-modifiable risk factors of coronary heart disease such as sex, age, family history and consanguineous marriage.

Methods: This is a case-control study.