[Inner ear and diabetes mellitus studies on 660 patients].

The purpose of this study was to examine the existence of any hearing loss typical of diabetes mellitus. 660 patients were interviewed by means of a questionnaire with regard to case history and the course of their disease. Internal and ophthalmological findings were registered which were compiled during clinical treatment for metabolic stabilisation.

[HLA association of insulin-dependent diabetes mellitus type I (author's transl)].

HLA antigens A, B, C, DR and BF were determined in 14 sibling pairs with type I diabetes and in 61 patients without familial risks. Significantly positive associations of the disease with HLA DR3 and DR4 and a negative association with DR2 were found. Positive and negative associations with the various HLA A, B and C antigens (A1, A2, B8, B15, B18, Cw3) are of a secondary nature due to strong genetic coupling with primarily associated DR alleles.