MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies.

Background: Radiofrequency ablation (RFA) is an efficient treatment with unlimited potential for liver cancer that can effectively reduce patient mortality. Understanding the biological process related with RFA treatment is important for improving treatment strategy. This study aimed to identify the critical targets for regulating the efficacy of RFA.

Hemolysis After Pulsed-Field Ablation of Atrial Fibrillation.

Pulsed-field ablation (PFA) offers notable advantages in atrial fibrillation (AF) ablation by selectively targeting cardiomyocytes via an irreversible electroporation mechanism, thereby minimizing damage to surrounding tissues. Although clinical studies demonstrate that PFA is both safe and effective, PFA-mediated hemolysis and potential acute kidney injury (AKI) development have been recently reported. This study comprehensively reviews the literature on PFA-associated hemolysis, analyzing the underlying mechanisms, risk factors, and preventive management strategies.

Identification of the Granule-Bound Starch Synthase (GBSS) Genes Involved in Amylose Biosynthesis in Tartary Buckwheat ( (L.) Gaertn.).

Tartary buckwheat is a nutrient-rich pseudo-cereal whose starch contents, including amylose and amylopectin contents, and their properties hold significant importance for enhancing yield and quality. The granule-bound starch synthase (GBSS) is a key enzyme responsible for the synthesis of amylose, directly determining the amylose content and amylose-to-amylopectin ratio in crops. Although one has already been cloned, the genes at the genome-wide level have not yet been fully assessed and thoroughly analyzed in Tartary buckwheat.

Megoura crassicauda promote the ability of Vicia faba L. to remediate cadmium pollution of water and soil.

With the increasing severity of heavy metal pollution in soil and water, phytoremediation is becoming increasingly popular because of its low cost, high returns, and environmental friendliness. The use of leguminous plants such as the broad bean for heavy metal remediation is becoming a research hotspot because of their symbiotic relationship with rhizobia. This study investigated the cadmium (Cd) remediation ability of fava beans by M.