[Morphofunctional characterization of Apud cells in the human rectum in tumor growth].

Under normal conditions the number and proportion of four main cell types of Apud cells (EC, DI, D, L) is stable. The number of Apud cells is always lower when adenomas or adenocarcinomas are present. A decrease of Apud cells number is inversely proportional to the degree of dysplasia.

[Anaplastic thyroid carcinoma with osteoclast-like giant cells].

Rapidly growing thyroid tumour in a female of 70 is reported. Histologically, the structures of three types were distinguished: follicular adenoma, follicular-solid form of the follicular adenoma and poorly differentiated tumour with presence of osteoclast-like cells. The latter were shown to contain an immunoreactive thyroglobulin.

[Brunner's gland adenoma of the duodenal bulb].

This rare tumor was found at surgery in a 35-year-old male operated for chronic ulcer of the duodenum complicated by gastrointestinal bleeding. The tumor looked like a pedunalated polyp 6 x 3 x 2 cm in size with an ulcer 0.5 cm in diameter.

[Apudoma of the prostate].

Prostatic apudomas are represented by well-, moderately- and poorly differentiated variants. Histologic differentiation determines various functional properties of tumor cells. Tumor cells of well-differentiated apudomas produce serotonin, less frequently calcitonin, poorly differentiated ones produce only ACTH.