Identification of light sensitivities, manifesting either as hyper-sensitive (over-stimulating) or hypo-sensitive (under-stimulating) in children with autism spectrum disorder (ASD), is crucial for the development of personalized sensory environments and therapeutic strategies. Traditional methods for identifying light sensitivities often depend on subjective assessments and manual video coding methods, which are time-consuming, and very keen observations are required to capture the diverse sensory responses of children with ASD. This can lead to challenges for clinical practitioners in addressing individual sensory needs effectively.
View Article and Find Full Text PDFThe lack of catalytic stereoselective approaches for producing 1,2--furanosides emphasizes the critical need for further research in this area. Herein, we present a stereoselective -furanosylation method, utilizing a 4,7-dipiperidine-substituted phenanthroline catalyst. This developed protocol fills a gap in the field, enabling the coupling of cysteine residues and thiols with furanosyl bromide electrophiles.
View Article and Find Full Text PDFPlastic polymers pose a significant challenge due to their resistance to degradation, resulting in their persistent accumulation in the environment and exacerbating a critical environmental concern. Urgent innovation and novel management technologies are essential to tackle this issue. Plastic biodegradation, distinguished by its environmentally friendly and safe attributes, has garnered substantial attention as a viable solution.
View Article and Find Full Text PDFThe human gut microbiota plays a crucial role in maintaining overall health. However, the widespread use of antibiotics has raised concerns about its impact on the microbial ecosystem. This review explores the multifaceted relationship between antibiotics and gut dysbiosis, highlighting the mechanisms underlying these interactions and their implications for human health.
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