Dysglycemia predicts cardiovascular and kidney disease in the Kidney Early Evaluation Program.

The cardiometabolic syndrome has been associated with both chronic kidney disease (CKD) and cardiovascular disease (CVD). Using data from the National Kidney Foundation-Kidney Early Evaluation Program, the authors sought to investigate this association in a targeted CKD cohort. A total of 26,992 patients met eligibility criteria including age 18 years and older, diabetes, hypertension, or family history of CKD, diabetes, or hypertension and excluded those taking renal replacement therapy.

A series of unusual complications of the presternal peritoneal dialysis catheter.

An ongoing problem for peritoneal dialysis (PD) patients has been complications associated with an indwelling PD catheter. The indwelling catheter has been through many modifications aimed at reducing complications and providing effective delivery of dialysis solution. In this report, we review four cases of rare complications associated with presternal PD catheters and a brief review of the Tenckhoff, Toronto Western Hospital, and Missouri swan-neck abdominal and presternal PD catheters.

Renin-angiotensin-aldosterone system intervention in the cardiometabolic syndrome and cardio-renal protection.

The metabolic syndrome, also known as the cardiometabolic syndrome (CMS), is a state of metabolic and vascular dysregulation that is associated with activation of the renin-angiotensin-aldosterone system (RAAS). Clinical components of the CMS include central or visceral obesity, hypertension (HTN), dyslipidemia, insulin resistance/hyperinsulinemia, and microalbuminuria that collectively convey increases in oxidative stress, inflammation, and subsequent endothelial dysfunction. The cardio-renal inflammation and oxidative stress enhanced in the CMS increases the risk for cardiovascular disease (CVD) and renal disease end-points such as stroke, congestive heart failure, and chronic kidney disease (CKD).

Obesity and insulin resistance as risk factors for chronic kidney disease.

The cardiometabolic syndrome is a state of metabolic and vascular dysregulation. The cardiometabolic syndrome is clinically composed of a cluster of metabolic abnormalities including insulin resistance/hyperinsulinemia, central/visceral obesity, dyslipidemia, hypertension, microalbuminuria, fibrinolytic and inflammatory abnormalities, endothelial dysfunction, oxidative stress, and hypercoagulability, which collectively lead to an increased risk of cardiovascular and renal outcomes. The development of microalbuminuria is now accepted as a marker of systemic endothelial dysfunction and, if it progresses to macroalbuminuria (i.

Exploratory study of suspended sediment concentrations downstream of harvested peat bogs.

Peat bog harvesting is an important industry in many countries, including Canada. To harvest peat, bogs are drained and drainage water is evacuated towards neighboring rivers, estuaries or coastal waters. High suspended sediment concentrations (SSC) were found in the drainage water at one particular site during the 2001-2002 spring seasons in New Brunswick (Canada).