Extracorporeal membrane oxygenation (ECMO) can support patients with severe cardiorespiratory failure presenting with hypoxia who would otherwise have not survived. Patient selection for ECMO is challenging and relies on the integration of physiological variables with an assessment of reversibility of the underlying condition or suitability for transplantation. In this review, we focus on patients with cardiorespiratory disease who may present with severe hypoxia.
View Article and Find Full Text PDFAntimicrobial resistance (AMR) is one of the top 10 global public health threats. One Health approach is needed to tackle antimicrobial resistance as most antimicrobials used in animals are also used in humans and affect the environment. Although the knowledge and attitudes of personnel in the human healthcare sector are studied more frequently in Gujarat, veterinarians' approaches also play a pivotal role in attaining antimicrobial stewardship.
View Article and Find Full Text PDFThe field of artificial intelligence (AI) has entered a new cycle of intense opportunity, fueled by advances in deep learning, including generative AI. Applications of recent advances affect many aspects of everyday life, yet nowhere is it more important to use this technology safely, effectively, and equitably than in health and health care. Here, as part of the National Academy of Medicine's Vital Directions for Health and Health Care: Priorities for 2025 initiative, which is designed to provide guidance on pressing health care issues for the incoming presidential administration, we describe the steps needed to achieve these goals.
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January 2025
Cancer treatment has evolved significantly over the years, incorporating a range of modalities including surgery, radiation, chemotherapy, and immunotherapy. However, challenges such as drug resistance, systemic toxicity, and poor targeting necessitate innovative approaches. Peptides have gained attention in cancer therapy due to their specificity, potency, and ability to modulate various biological pathways.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Basis Dis
January 2025
Cancer-associated cachexia (CAC) is a debilitating condition, observed in patients with advanced stages of cancer. It is marked by ongoing weight loss, weakness, and nutritional impairment. Lower tolerance of chemotherapeutic agents and radiation therapy makes it difficult to treat CAC.
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