Decision formation in perceptual decision making involves sensory evidence accumulation instantiated by the temporal integration of an internal decision variable toward some decision criterion or threshold, as described by sequential sampling theoretical models. The decision variable can be represented in the form of experimentally observable neural activities. Hence, elucidating the appropriate theoretical model becomes crucial to understanding the mechanisms underlying perceptual decision formation.
View Article and Find Full Text PDFComput Brain Behav
January 2024
Unlabelled: Sequential sampling models of decision-making involve evidence accumulation over time and have been successful in capturing choice behaviour. A popular model is the drift-diffusion model (DDM). To capture the finer aspects of choice reaction times (RTs), time-variant gain features representing urgency signals have been implemented in DDM that can exhibit slower error RTs than correct RTs.
View Article and Find Full Text PDFPatients on warfarin who have traumatic intracranial haemorrhage have a high mortality. The procoagulant recombinant factor VIIa (rFVIIa) is widely used off-label to treat intracranial haemorrhaging in patients taking warfarin to try to improve these adverse outcomes, but its effectiveness is unknown. In this study, medical records from 2002 to 2010 were reviewed for 27 warfarin patients who received rFVIIa for their traumatic intracranial haemorrhage and were compared with a matched control group of 27 warfarin patients who did not receive rFVIIa.
View Article and Find Full Text PDFBackground: Injuries and deaths among riders of off-road motorized all-terrain vehicles are increasing in the US. We hypothesized that serious injuries in Oregon have increased among riders of both four-wheel and two-wheel vehicles.
Study Design: We analyzed the Oregon Trauma Registry.