Publications by authors named "B S Hurwitz"
Cisgender women living with HIV experience elevated cardiovascular disease (CVD) risk that increases with age, a concern given extended life expectancies for people living with HIV. The CVD risk disparity among cisgender women aging with HIV is understudied and remains unclear. Taking a psychoneuroimmunology approach, given this group's intersecting marginalized identities, one potential driver of the disparity is intersectional stigma.
View Article and Find Full Text PDFComparison of k-mer-based comparative metagenomic tools and approaches.
Microbiome Res Rep
July 2023
Comparative metagenomic analysis requires measuring a pairwise similarity between metagenomes in the dataset. Reference-based methods that compute a beta-diversity distance between two metagenomes are highly dependent on the quality and completeness of the reference database, and their application on less studied microbiota can be challenging. On the other hand, comparative metagenomic methods only rely on the sequence composition of metagenomes to compare datasets.
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- Hypertensive disorders of pregnancy (HDP) are linked to long-term cardiovascular risks for women, though the reasons are not fully understood.
- A study involving 5,168 Hispanic/Latina women revealed that 14% had a history of de novo HDP, which was associated with lower left ventricle ejection fraction and higher risks of abnormal cardiac geometry.
- Findings indicate that previous HDP can lead to measurable cardiac issues in women, with current hypertension only partially explaining these effects.
Background: The proliferation of metagenomic sequencing technologies has enabled novel insights into the functional genomic potentials and taxonomic structure of microbial communities. However, cyberinfrastructure efforts to manage and enable the reproducible analysis of sequence data have not kept pace. Thus, there is increasing recognition of the need to make metagenomic data discoverable within machine-searchable frameworks compliant with the FAIR (Findability, Accessibility, Interoperability, and Reusability) principles for data stewardship.
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- * Researchers conducted a spatial survey using an underwater vehicle in a specific area of the Ross Ice Shelf, revealing ice melting and freezing dynamics in the basal crevasse.
- * Findings indicate that these basal crevasses significantly alter ocean circulation and mixing at grounding zones, suggesting a complex interaction previously underestimated.