Publications by authors named "B S Blake Perdikis"

Article Synopsis
  • Leptomeningeal carcinomatosis (LMC) is a severe complication in 5-15% of stage IV cancer patients, currently having a poor median overall survival of 2-6 months due to ineffective treatments.
  • A systematic review analyzed 43 clinical trials from 1982-2022, finding that most were non-randomized and focused on various primary tumors, with a significant number closing due to low patient enrollment.
  • Intraventricular/intrathecal drug delivery was the most common treatment method, and findings indicate a need for a shift towards targeted systemic therapies to improve survival rates.
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Introduction: Although neurotization has the potential to improve sensory outcomes after autologous breast reconstruction, this technique remains controversial. There is debate regarding the clinical outcomes and the recipient nerve of choice. This histoanatomical study aims to quantitatively compare the sensory components of the recipient nerves involved in neurotization of the deep inferior epigastric perforator flap.

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Objective: Olfactory disturbance is a common complication that occurs following the surgical resection of olfactory groove meningiomas (OGMs). There is little evidence on the best transcranial approach that minimizes rates of postoperative olfactory disturbance. The objective of this systematic review and meta-analysis is to compare smell outcomes after OGM resection in unilateral versus bilateral transcranial approaches.

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