Publications by authors named "B S Alabi"
Article Synopsis
- Red cell distribution width (RDW) is a measure of variability in red blood cell sizes and may indicate cardiovascular disease (CVD) risk, especially in low-resource areas, according to a study in Ghana and Nigeria.
- The study involved 319 adults with hypertension who underwent assessments like blood pressure and RDW measurement, revealing an average RDW of 13.96% and a median CVD risk score of 8.11%.
- Findings showed that RDW is positively correlated with age, systolic and diastolic blood pressure, and WHO CVD risk scores, suggesting RDW could be a useful predictor of CVD risk in this population, particularly with an RDW cutoff of >14
Evaluation of Hippocampal Microanatomy and Neuro-Biomarkers Following Administration of Silver Nanoparticles Conjugated with Tenofovir Disoproxil Fumarate in Experimental Diabetic Rats.
Pharmaceuticals (Basel)
December 2024
Adverse complications like metabolic disorders, neurotoxicity, and low central nervous system (CNS) penetration are associated with the long-term use of tenofovir disoproxil fumarate (TDF). Therefore, some modifications are required to enhance neurological functions using silver nanoparticles (AgNPs). This study aimed to evaluate the neuroprotective impact of silver nanoparticles (AgNPs)-conjugated TDF as AgNPs-TDF on the hippocampal microanatomy and some neuro-biomarkers of diabetic rats.
View Article and Find Full Text PDFIntroduction: Sedentary lifestyle and consumption of an unhealthy diet are significantly associated with hypertension in Nigeria and Ghana. Increasing the uptake of physical activity and diet rich in fruits and vegetables has been a challenge in the region. This study aimed at assessing the effect of a mobile health intervention (mhealth) on physical activity, and fruits and vegetables intake in patients with hypertension in Nigeria and Ghana.
View Article and Find Full Text PDFBackground: Ischemia-reperfusion injury (IRI) is unavoidable during kidney transplant and it is responsible for delayed or non-function after kidney transplantation. Cysteamine is the standard drug in the management of nephropathic cystinosis and its extra-renal complications. Thus, we designed this study to investigate its potential against renal reperfusion injury.
View Article and Find Full Text PDFContext: The mucociliary clearance system is an important component in the prevention of chronic inflammation of the nasal and paranasal sinus.
Aim: The study aims to establish the normal values of mucociliary clearance in our region and to study the variation in mucociliary activity in patients with chronic rhinosinusitis in Ilorin, North-central Nigeria.
Settings And Design: This was a prospective, cross-sectional study using consecutive consenting participants in both the control and study groups carried out at both family medicine and otorhinolaryngology clinics among patients attending the clinics.