Publications by authors named "B Rueda"
Background: Patients with secondary acute myeloid leukemia who previously received hypomethylating agents for prior myeloid neoplasms (HMA-sAML) face a dismal prognosis.
Methods: The authors analyze the characteristics, therapeutic approaches, and outcomes of patients with HMA-sAML from the Programa Español para el Tratamiento de Hemopatías Malignas (PETHEMA) registry.
Results: A total of 479 patients were included, mostly from prior myelodysplastic syndrome (84%).
Article Synopsis
- * Researchers tested the anti-hypertensive drug losartan in ovarian cancer models, discovering that it improves the tumor microenvironment and enhances drug delivery and immune cell activity while also making cancer cells more sensitive to chemotherapy.
- * Given its safety and low cost, losartan could be a promising addition to treatments for ovarian cancer, potentially improving outcomes for patients.
Article Synopsis
- * Researchers found that extracellular vesicles (EVs) are produced in higher amounts in LAM and carry specific proteins that enhance LAM cell movement and invasion.
- * The study suggests that EVs play a crucial role in LAM metastasis by modifying cell behavior and promoting lung metastasis, highlighting potential new targets for LAM treatments.