Publications by authors named "B Rosario"

Purpose: The C4 dermatome anesthesia holds significance for arthroscopic shoulder surgery. However, the reliability of achieving C4 dermatome anesthesia with the current low-dose ultrasound-guided interscalene block (ISB) and supraclavicular block (SCB) remains uncertain. This prospective, single-center study examined the effects of ultrasound-guided interscalene block (ISB) and supraclavicular block (SCB) on the C4 sensory dermatome in patients undergoing shoulder, hand, or wrist surgery.

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  • The study investigates the effectiveness of the modified Hospital Frailty Risk Score (mHFRS) in identifying frail hospitalized older adults, comparing it with the original Hospital Frailty Risk Score (HFRS) and the Clinical Frailty Scale (CFS).
  • A review of 3,042 patients over 65 years old was conducted, revealing that the CFS identified 46.3% as frail, with frail patients generally being older, more likely female, and having longer hospital stays and higher mortality rates.
  • The mHFRS showed a significant correlation with both CFS and HFRS, proving to be effective in classifying patients, especially identifying non-frail individuals, and suggesting it as a
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  • * Certain pathogens, like HIV, malaria, and SARS-CoV-2, can hinder the transfer of these protective antibodies from mother to child, affecting neonatal health.
  • * The review highlights changes in antibody characteristics, maternal immune responses, and placental damage as factors that impact antibody transfer, stressing the importance of understanding these processes for better pandemic preparedness and child health outcomes.
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Objective: To determine if the recurrence rates of BPPV in older adults were lower in the vitamin D-treated group as compared to placebo groups.

Study Design: Double-blinded randomized control placebo trial.

Setting: A single-centre study.

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Background: With the recent Food & Drug Administration (FDA) approval of cellular therapy that requires product manipulation prior to administration in combination with a short stability window, the need was identified for local dose preparation within the pharmacy rather than the off-site stem cell processing laboratory. This approval gave rise to assessment of regulatory standards surrounding cellular therapy, evaluation and revision of current standard operating procedures and policies with formal process validation, assessment of occupational exposure mitigation and safety considerations, and development of staff training and education.

Objective: To describe and provide insight into the stepwise process of FACT validation and onboarding of commercially available cellular therapy products that require sterile compounding manipulation within a pharmacy prior to administration.

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