Publications by authors named "B Roper"
the parasite responsible for nearly all cases of severe malaria, must survive challenging environments to persist in its human host. Symptomatic malaria is characterized by periodic fevers corresponding to the 48-hour asexual reproduction of in red blood cells. As a result, has evolved a diverse collection of heat shock proteins to mitigate the stresses induced by temperature shifts.
View Article and Find Full Text PDFBackground: Performance validity (PV) and symptom validity (SV) tests assess biased responding that impact scores on neuropsychological tests. The extent to which PV and SV represent overlapping or unique constructs remains incompletely defined, especially among psychiatric patients in a non-forensic setting. The current study investigated this question using confirmatory factor analysis.
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- * The study produced various mRNAs using different engineered T7 RNA polymerases to analyze key properties like integrity and functional activity, particularly focusing on impurities that could affect therapeutic efficacy.
- * Findings emphasize the need for sophisticated analytical methods to better characterize mRNA impurities and their effects on cellular responses, which is crucial for ensuring the safety and effectiveness of RNA-based treatments.
Introduction: Pediatric pelvic and acetabular fractures are rare but potentially devastating injuries and significant management variation exists across the United States. This study sought to elucidate treatment decision-making trends, involvement of adult trauma fellowship-trained surgeons in pediatric care, and pre- and postoperative transfer patterns.
Methods: Pediatric orthopaedic surgeons who serve as trauma liaisons at 20 PTCs were surveyed regarding training, practice volume, and factors contributing to institutional management of pelvic and acetabular injuries.
Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States.
J Pediatric Infect Dis Soc
November 2024
Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.
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