Publications by authors named "B Rohaut"
Attention shapes our consciousness content and perception by increasing the probability of becoming aware and/or better encoding a selection of the incoming inner or outer sensory world. Engaging interoceptive and exteroceptive attention should elicit distinctive neural responses to visceral and external stimuli and could be useful in detecting covert command-following in unresponsive patients. We designed a task to engage healthy participants' attention toward their heartbeats or auditory stimuli and investigated whether brain dynamics and the heartbeat-evoked potential (HEP) distinguished covert interoceptive-exteroceptive attention.
View Article and Find Full Text PDFProbing cognition and consciousness in the absence of functional communication remains an extremely challenging task. In this perspective, we imagined a basic clinical procedure to explore pain anticipation at bedside. In a series of 61 patients with a disorder of consciousness, we tested the existence of a nociceptive anticipation response by pairing a somaesthetic stimulation with a noxious stimulation.
View Article and Find Full Text PDFArticle Synopsis
- - Disorders of consciousness (DoC) are complex neurological conditions with limited treatment options, leading to interest in new therapies like psychedelics.
- - Researchers combined whole-brain models and deep learning to study how pharmacological interventions affect brain dynamics in DoC patients.
- - The study found that targeting serotonergic and opioid receptors could promote healthier brain states, suggesting potential treatments for DoC and other brain disorders while adhering to ethical research guidelines.
Background: Patients with brain injury who are unresponsive to commands may perform cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). This phenomenon, known as cognitive motor dissociation, has not been systematically studied in a large cohort of persons with disorders of consciousness.
Methods: In this prospective cohort study conducted at six international centers, we collected clinical, behavioral, and task-based fMRI and EEG data from a convenience sample of 353 adults with disorders of consciousness.