Successful treatment of radiation cystitis with hyperbaric oxygen.

This report describes the results of hyperbaric oxygen therapy in 10 patients with radiation-induced cystitis. Severe macroscopic hematuria was present in all patients and was resistant to current therapy. Previously 8 patients had been treated for bladder carcinoma and 2 for prostatic carcinoma with 60 Gy radiotherapy.

Six-day canine kidney preservation. Hypothermic perfusion combined with isolated blood perfusion.

Successful 6-day kidney preservation was obtained with a combination of perfusion techniques. Canine kidneys were preserved by hypothermic continuous perfusion in a Gambro machine with albumin perfusate. On day 3 the hypothermic preservation was interrupted by a normothermic perfusion for 3 hr.

Six-day kidney preservation in a canine model. Influence of a one-to-four-hour ex vivo perfusion interval.

Continuous hypothermic perfusion (CHP) was improved when interrupted by an interval of ex vivo perfusion. The influence of the length (1-4 hr) of this interval of ex vivo perfusion was studied in a dog model. Kidneys were subjected to CHP for 72 hr, then connected with the donor for 1, 2, 3, and 4 hr, then returned to CHP and, after a total preservation time of 144 hr, autotransplanted.

Functional studies in 6 days successful preserved canine kidneys.

In 2 groups of 6 dogs each the right kidney was removed, flushed with Collins and then perfused in a Gambro preservation machine for 6 days. After this period the kidneys were reimplanted in the neck of the subsequently nephrectomized donor. The only difference in Group 2 was that halfway the 6-day hypothermic perfusion the kidneys were taken from the machine and perfused ex vivo for 3 hours by connections with the femoral vessels of the same donor dog.