Uncertainties in the expected value for forced expiratory volume in one second after surgery.

The purpose of this study is to understand better the reasons for the frequent unreliability of the expected value for the forced expiratory volume in one second (FEV1) in predicting surgical results after pneumonectomy. Measurement of FEV1 was performed in 159 patients before and after removal of one lung. Only 41 of the postoperative values for FEV1 differed from predicted values by less than 5 percent.

Effects of sitting up on pulmonary blood pressure, flow, and volume in man.

Pulmonary vascular pressure, blood flow, and blood volume were measured in the supine and sitting positions in eight subjects with localized lung carcinoma associated with moderate airway obstruction. Supine cardiac output, pulmonary wedge (Ppw) and artery (Ppa) pressure, and pulmonary vascular resistance (PVR) were normal. Circulatory changes in sitting position were also normal: heart rate increased 13 +/- 9% (mean +/- SD); stroke volume fell 21 +/- 15%; cardiac output fell 13 +/- 19%; and arteriovenous O2 difference increased 37 +/- 21%.