Publications by authors named "B Rajendran"
Background: Endophenotypes aid in studying the complex genetic basis of bipolar disorder. We aimed to compare first-degree relatives of patients with bipolar I disorder in a hospital in India with unrelated healthy controls in terms of neurocognition and affective temperament METHODS. This cross-sectional study was conducted between August and November 2012 at a tertiary hospital in India.
View Article and Find Full Text PDFAngiopoietin-like 4 (ANGPTL4), a key protein involved in lipoprotein metabolism, has diverse effects. There is an association between Angptl4 and diabetic kidney disease; however, this association has not been well investigated. We show that both podocyte- and tubule-specific ANGPTL4 are crucial fibrogenic molecules in diabetes.
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- Advances in cancer treatment, especially for breast cancer, have been made through the identification of specific biomarkers and the use of high-throughput sequencing technology.
- While precision medicine can help some patients by targeting actionable mutations, not all breast cancer patients benefit equally from these approaches.
- The review highlights the importance of understanding breast cancer driver mutations, as this knowledge fosters the development of targeted therapies that, alongside traditional treatments, can improve patient outcomes and survival rates.
Statement Of The Problem: Conventional injection technique with adrenaline during removal of impacted third molar of mandible had proportionally increased pain during administration with slow onset of action and shorter duration of anesthesia.
Purpose: The purpose of this study was to compare the effective nature of 8.4% and 7.
Purpose: Clinical research trials are needed to enhance the medical care and treatment for lung cancer, which remains the leading cause of cancer-related deaths worldwide. While clinical trials allow for the development of novel therapies to treat cancer, the recruitment of lung cancer patients to trials is low. This review aimed to identify and synthesise the available literature concerning barriers and facilitators affecting lung cancer patients' decisions to enrol in clinical trials to guide future cancer research efforts.
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