Anticancer Agents Med Chem
September 2022
Background: Lung tumors express high levels of aromatase enzyme compared to surrounding normal tissue. Inhibition of aromatase has emerged as a recent therapeutic approach for the treatment of breast cancer. However, the role of aromatase inhibition in lung cancer treatment requires further investigation.
View Article and Find Full Text PDFVaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare complication after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adenoviral vector vaccination. In British Columbia (BC), Canada, a provincial clinical care pathway was developed to guide clinicians in evaluating for VITT among patients who present with thrombocytopenia or thrombosis symptoms within 4 to 28 days after adenoviral vector vaccine exposure. All patients had enzyme-linked immunosorbent assay (ELISA) testing for platelet factor 4 (PF4) antibodies, and all cases with positive PF4-ELISA or d-dimer levels ≥2.
View Article and Find Full Text PDFUnder some assumptions on the nonlinearity , we will study the nonexistence of nontrivial stable solutions or solutions which are stable outside a compact set of [Formula: see text] for the following semilinear higher-order problem: [Formula: see text] with [Formula: see text]. The main methods used are the integral estimates and the Pohozaev identity. Many classes of nonlinearity will be considered; even the sign-changing nonlinearity, which has an adequate subcritical growth at zero as for example [Formula: see text], where [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text].
View Article and Find Full Text PDFIntroduction And Objectives: The American University of Beirut Faculty of Medicine (AUB-FM) strategy is to develop faculty members (fm) skills by sponsoring local and international scientific activities has been in place for over three decades, and remains dependent on individuals' efforts. In 2011-2012, Faculty Development Program (FDP) was introduced to develop faculty leadership, business skills in medicine, fulfill personal and professional goals, followed by a five-year plan to cover five themes: Management/Leadership, Marketing, Finance, Strategic Planning and Communications with the purpose of integrating these themes in medical practice.
Methods: A survey was sent to all departments at AUB-FM in 2011 to assess needs and determine themes.