Publications by authors named "B R Shome"
Detection of anti-leptospiral antibodies using recombinant ErpY-like lipoprotein based latex agglutination test for serodiagnosis of animal leptospirosis.
Lett Appl Microbiol
November 2024
Article Synopsis
- Timely diagnosis of leptospirosis is crucial for preventing severe health outcomes in both humans and animals, and current diagnostic methods have limitations that necessitate new approaches.
- This study explores a novel diagnostic tool using a recombinant lipoprotein (rErpY-LIC11966) in a latex agglutination test (LAT), which was developed and tested for its effectiveness in diagnosing animal leptospirosis.
- The rErpY-LAT demonstrated high diagnostic performance, with 90.6% sensitivity, 89.1% specificity, and 90% overall accuracy, making it a promising field-applicable option for early serodiagnosis of the disease.
Article Synopsis
- Leptospirosis and dengue are major health concerns in the Dakshina Kannada district of Karnataka, India, where both diseases are understudied and have significant health risks.
- The study aimed to determine the prevalence of these diseases among people with febrile illnesses and assess co-infection rates during 2020-2021.
- Results indicated that 21% of febrile cases had leptospirosis and 10% had dengue, with a low co-infection rate of 1.3%, emphasizing the need for better public health strategies and diagnostic tools in the region.
Leptospirosis is a significant zoonotic disease affecting livestock, leading to reproductive issues and economic losses. Despite its endemic status in India, research has predominantly focused on coastal regions, leaving the North Eastern Region (NER) underexplored. This study aims to investigate the seroprevalence and serogroup distribution of leptospirosis in livestock across Assam, a major state in the North Eastern Region (NER) of India.
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- Mannheimia haemolytica is a key pathogen in pneumonic pasteurellosis, causing significant economic losses for small ruminant farmers, but its epidemiology is under-researched, complicating control efforts.
- A study characterized 27 M. haemolytica isolates via capsular typing and various molecular methods, revealing that serotype A2 was the most prevalent (74%), with specific virulence genes being widely present.
- The research identified 11 sequence types (STs), including new ones, and showed high variability among isolates, indicating the complexity of managing this disease in sheep.
Flock level socio-economic and other associated risk factors for Peste des petits ruminants (PPR) exposure in sheep and goats in Madhya Pradesh state, India.
Trop Anim Health Prod
April 2024
To effectively control and eradicate PPR, the comprehensive understanding of risk factors associated with PPR exposure is vital. Hence, this study investigated socioeconomic and other associated risk determinants for PPR exposure at flock level in sheep and goats in a non-vaccination programme implemented Madhya Pradesh state India. A total of 410 sheep and goat flocks, comprised mostly of goats but also some mixed flocks, were surveyed during 2016 using a multistage random sampling procedure.
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