Publications by authors named "B R Rowe"
Background: Understanding the sequential progression of cognitive decline in autosomal dominant Alzheimer's disease (ADAD) in the Latino population is crucial for enhancing early identification for targeted interventions. Given the tablet-based administration and increasing frequency of use in epidemiological research, validating this progression within the NIH Toolbox cognitive battery (NIHTB-CB) is important.
Objective: The first aim was to utilize an innovative Event-Based Modeling (EBM) analytic approach to estimate the sequence of cognitive declines in persons at risk for ADAD enriched for being of Latino origin.
Background: The objective of this study was to assess the health outcomes for patients who present to the emergency department (ED) with cardiac chest pain after the implementation of an accelerated diagnostic protocol using a high-sensitivity troponin assay (hs-TnI).
Methods: This prospective before-after cohort study used population-based linked health administrative data for adult patients who presented to a Canadian urban ED with chest pain of suspected cardiac origin over a 2-year study period. The primary outcome was ED length of stay (LOS).
Context: Reducing unnecessary imaging in emergency departments (EDs) for children with minor traumatic brain injuries (mTBIs) has been encouraged.
Objective: Our objective was to systematically review the effectiveness of interventions to decrease imaging in this population.
Data Sources: Eight electronic databases and the gray literature were searched.
Article Synopsis
- There has been a rise in accelerated diagnostic protocols (ADPs) and high-sensitivity troponin assays (hsTn) used in emergency departments for evaluating chest pain, which was the focus of this study.
- This research analyzed 37 studies involving over 404,000 patients and found significant reductions in emergency department length of stay (LOS) after implementing ADPs, particularly in departments with longer initial LOS.
- While some studies showed an increase in patient admissions after ADP implementation, many reported a decrease, and there was no increase in major adverse cardiac events (MACE) within 30 days post-assessment.