Modeling BK Virus Infection in Renal Transplant Recipients.

Kidney transplant recipients require a lifelong protocol of immunosuppressive therapy to prevent graft rejection. However, these same medications leave them susceptible to opportunistic infections. One pathogen of particular concern is human polyomavirus 1, also known as BK virus (BKPyV).

Weaving the strands together for a stronger future: Responding to the mental health needs of Pacific children and young people.

Objective: The aim of this paper is to summarise the findings of a virtual workshop at the Creating Futures 2023 Conference held on October 18 with 45 participants attending from Fiji, PNG, Solomon Islands, the Federated States of Micronesia, Cook Islands, Australia and New Zealand. Brief presentations about future mental health needs of Pacific children & young people were followed by small group discussions. These focussed on how island nation participants could "make it real" by considering actions to promote mental health and wellbeing in their communities.

Drought-Induced Weakening of Temperature Control on Ecosystem Carbon Uptake Across Northern Lands.

Rapid warming in northern lands has led to increased ecosystem carbon uptake. It remains unclear, however, whether and how the beneficial effects of warming on carbon uptake will continue with climate change. Moreover, the role played by water stress in temperature control on ecosystem carbon uptake remains highly uncertain.

Primary Peristalsis Is the Dominant Mechanism of Refluxate Clearance Following Gastroesophageal Reflux.

Background: Refluxate volume and pH drop following gastroesophageal reflux are mostly cleared by peristalsis. We evaluated the roles of primary volume clearing peristaltic wave (VCPW), secondary VCPW, post-reflux swallow-induced peristaltic wave (PSPW), and late primary peristaltic wave (LPPW) in refluxate clearance.

Methods: We retrospectively analyzed pH-impedance studies performed off therapy in 40 patients with typical esophageal symptoms.

Facilitator development for pre-registration health professions simulation: a scoping review protocol.

Introduction: The growing demand for health professional education intensifies the need for learning innovations such as simulation: facilitating predictable, realistic, experiential learning that prepares students for practice. To achieve this, facilitators must provide pedagogically sound, psychologically safe simulation. High-quality simulation enhances students' self-efficacy, critical thinking, and clinical reasoning.