Digital monitoring of medication safety in children: an investigation of ADR signalling techniques in Malaysia.

Background: Digital solutions can help monitor medication safety in children who are often excluded in clinical trials. The lack of reliable safety data often leads to either under- or over-dose of medications during clinical management which make them either not responding well to treatment or susceptible to adverse drug reactions (ADRs).

Aim: This study investigated ADR signalling techniques to detect serious ADRs in Malaysian children aged from birth to 12 years old using an electronic ADRs' database.

Pancreatic Choristoma in Omentum in Advanced CA Ovary: A Clinical Puzzle.

Ectopic pancreatic tissue is called pancreatic choristoma or heterotopia of pancreas. It is a rare entity. We present a case of advanced Ca ovary with omental pancreatic choristoma.

Comparative Evaluation of Salivary and Serum High-Sensitive C-Reactive Protein in Acute Myocardial Infarction.

Aim: The aim of this study is to comparatively evaluate the serum and salivary high-sensitive C-reactive protein (hs-CRP) in patients with acute myocardial infarction (MI).

Subjects And Methods: The study group consisted of 60 patients of whom 30 were MI patients and 30 were controls. Serum hs-CRP was assessed using particle-enhanced immunoturbidimetric assay.

Association of Agriculture Occupational Exposure With Diabetes and Cardiovascular Risk Factors in South Indian Villages: REDSI Study.

There has been a huge increase in diabetes and its associated cardiovascular complications over the last decade, predominantly in the middle- and low-income countries. In these countries, the majority live in rural areas. The Rural Epidemiology of Diabetes in South India (REDSI) study was aimed to analyze the prevalence of diabetes, cardiovascular risk factors, and its complications in rural farming and non-farming villages in Tamil Nadu, South India.

Context-Dependent Regulation of Nrf2/ARE Axis on Vascular Cell Function during Hyperglycemic Condition.

Diabetes mellitus is associated with an increased risk of micro and macrovascular complications. During hyperglycemic conditions, endothelial cells and vascular smooth muscle cells are exquisitely sensitive to high glucose. This high glucose-induced sustained reactive oxygen species production leads to redox imbalance, which is associated with endothelial dysfunction and vascular wall remodeling.