Surgical and Pathological Results Following Neoadjuvant Nivolumab and Platinum-Based Chemotherapy for Locally Advanced Resectable NSCLC: A Multicentre Real-World Series From England.

Background: To evaluate the real-world surgical and pathological outcomes following neoadjuvant nivolumab in combination with chemotherapy in a multicentre national cohort of patients.

Methods: Retrospective analysis on consecutive patients treated in three tertiary referral hospitals in UK with neoadjuvant chemotherapy and immunotherapy (nivolumab) for stage II-IIIB nonsmall cell lung cancer (March 2023-May 2024). Surgical and pathological outcomes were assessed.

Preoperative smoking cessation interventions: a systematic review and meta-analysis.

Background: Smoking is the leading single cause of preventable death in England and also increases the risk of postoperative complications. The preoperative period is a potential opportunity to introduce smoking cessation interventions to smokers to reduce the risk of postoperative complications. A systematic search was conducted to find all studies that investigated the effectiveness of preoperative smoking cessation interventions.

Temporal variability of microplastics in shrimp (Litopenaeus vannamei), feed, water and sediments of coastal and inland culture ponds.

Aquaculture, particularly shrimp farming, is crucial for global food security. However, the increasing presence of microplastics (MPs) in marine environments, shrimp feeds, and atmospheric particles has made MP contamination in shrimp tissues inevitable. This study systematically investigates the abundance, characteristics, and temporal trends (from 15th to the 120th day of culture) of MPs contamination in Litopenaeus vannamei, along with associated feed, water, and sediment across 12 shrimp ponds of two major shrimp-producing regions of India.

Broadband Shortwave Infrared-Emitting Cr- and Ni-Codoped YAlGaO Phosphor with Excellent Thermal Stability for Multifunctional Applications.

Shortwave infrared (SWIR)-emitting materials have emerged as superior light sources with increasing demand for potential applications in noninvasive analysis, night vision illumination, and medical diagnosis. For developing next-generation SWIR phosphor-converted light-emitting diodes (pc-LEDs), the scarcity of intense blue-light-pumped broadband SWIR luminescent materials and poor thermal stability of current Ni-activated phosphors are the ongoing challenges. Here, a blue-light-excitable (440 nm) YAlGaO:Cr,Ni phosphor with ultrawide SWIR emission centered at ∼1430 nm (FWHM ∼264 nm) is reported.

Management of benign airway stenosis-predictors of tracheal resection.

Background: Benign airway stenoses are complex disorders that present with progressive dyspnoea, stridor, and significant respiratory distress. These conditions have a high recurrence rate and despite the plethora of endoscopic and open techniques available for treatment, the outcomes are variable. Our primary was to determine the pre-operative factors associated with an increased hazard of cricotracheal resection (CTR)/tracheal resection (TR) and reconstruction in cases of benign subglottic and tracheal strictures.