Publications by authors named "B R Kurt"

Background: Proenkephalin A 119-159 (penKid) is a novel blood biomarker for real-time assessment of kidney function and was found to be independently associated with worsening kidney function and mortality. A novel penKid-based estimated glomerular filtration rate equation (eGFR), outperforms current creatinine-based eGFR equations in predicting iohexol or iothalamate plasma clearance-based measured GFR. In this study, we aimed to evaluate the predictive value of penKid and eGFR for all-cause mortality in stable patients at high cardiovascular risk.

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Background: There are few studies in the literature comparing the effectiveness of topical treatments in early-stage mycosis fungoides (MF).

Objectives: It was aimed to evaluate the clinical efficacy, side effects and topical treatment compliance with bexarotene or clobetasol propionate in early-stage MF.

Methods: A total of 40 patients with stage IA-IB MF were enrolled in the study.

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Background: The impact of routine preoperative anesthesia evaluations on potential perioperative complications remains unclear. This study aimed to investigate the effect of preoperative evaluation on early perioperative hemodynamic and respiratory complications.

Methods: This prospective observational study analyzed data from patients aged 18 to 80 who underwent elective surgery between October 15, 2023, and February 15, 2024.

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Article Synopsis
  • - Ovarian cancer is typically diagnosed at advanced stages, and monoclonal antibodies (MAbs) targeting specific antigens are being utilized in treatment, with a focus on the Anti-Müllerian hormone receptor type 2 (AMHR2) as a potential therapeutic target.
  • - Researchers analyzed the 3D structure of AMHR2 and identified three peptide sequences (Peptides 1, 7, and 11) to produce monoclonal antibodies, generating six antibody clones with different affinities for these peptides.
  • - Among the produced MAbs, the P3B1 clone demonstrated significant cytotoxicity against SKOV-3 ovarian cancer cells, and its variable regions were sequenced for future development as a
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Purpose: To investigate systemic and ocular toll-like receptor (TLR)-4 expression and its association with oxidative stress markers in ocular rosacea (OR).

Methods: This prospective study included 40 patients with rosacea with ocular involvement and 20 healthy volunteers. Tear break-up time (TBUT), Schirmer test, meibomoscore, and ocular surface disease index (OSDI) scores were estimated for all participants.

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