Publications by authors named "B R Avalos"
: HIV-associated neurocognitive impairment (NCI) remains a prevalent issue among people with HIV (PWH) despite advancements in antiretroviral therapy (ART). The pathogenesis of HIV-associated NCI is linked to chronic neuroinflammation caused by HIV, even in those with successful viral suppression. Growth Differentiation Factor 15 (GDF15), a protein involved in inflammatory and metabolic stress responses, has emerged as a key player and potential biomarker for various neurological conditions.
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- * Between 2004 and 2022, MRI awarded scholarships to 405 individuals, and those who received funding had significantly lower dropout rates compared to national averages: 0% for graduate students and 2.2% for medical students.
- * The initiative also showed that awardees were more likely to stay in the hematology-oncology field than national minority averages, with 14.4% of medical students and 88.5% of early-career
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- - Venetoclax is an effective treatment for chronic lymphocytic leukemia (CLL) that can lead to long-lasting remissions but carries a risk of tumor lysis syndrome (TLS), which necessitates careful monitoring during treatment.
- - A study at Levine Cancer Institute examined 73 patients with CLL on venetoclax to determine how often TLS monitoring led to interventions, finding that strict adherence to monitoring occurred in 66% of cases.
- - Results showed a low incidence of TLS, with only one laboratory case reported and no clinical cases, indicating that most patients, especially those with low tumor burden, required few interventions.
Malignancy is a well-known risk factor for venous thromboembolism (VTE), and the Khorana risk score is effective for screening patients with solid tumors. However, there is a lack of validated screening tools and established risk factors for patients undergoing hematopoietic stem cell transplantation (HCT). Current literature reports a 2.
View Article and Find Full Text PDFTriggering receptor expressed on myeloid cells 2 (TREM2) is involved in neuroinflammation and HIV-associated neurocognitive impairment (NCI). People with HIV (PWH) using cannabis exhibit lower inflammation and neurological disorders. We hypothesized that TREM2 dysfunction mediates HIV neuropathogenesis and can be reversed by cannabinoids.
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