Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC).

Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S.

Redetection of human papillomavirus type 16 infections of the cervix in mid-adult life.

Purpose: To assess whether HPV 16 originally detected in adolescent women can be redetected in adulthood.

Methods: A convenience sample of 27 adult women with known HPV 16 detection during adolescence was assessed for HPV 16 redetection. A comparison of the long control region (LCR) DNA sequences was performed on some of the original and redetected HPV 16 isolates.

Invasive cervical cancers in the United States, Botswana and Kenya: HPV type distribution and health policy implications.

Background: More deaths occur in African women from invasive cervical cancer (ICC) than from any other malignancy. ICC is caused by infection with oncogenic types of human papillomavirus (HPV). Co-infection with the human immunodeficiency virus (HIV) accelerates the natural history of ICC, and may influence the HPV type distribution.

Episodic detection of human papillomavirus within a longitudinal cohort of young women.

Redetection of a type-specific human papillomavirus (HPV) infection may represent reinfection. However, a growing body of literature suggests that reactivation of HPV is common and that episodic detection of a HPV infection may represent reactivation of a persistent virus. A cohort of prospectively followed adolescent women (N = 150), ages 14-17, was observed on average 6.

Invasive cervical cancers from women living in the United States or Botswana: differences in human papillomavirus type distribution.

Background: Cervical cancer is the primary cause of cancer-related deaths in women living in Botswana.

Methods: Paraffin-embedded blocks of formalin-fixed invasive cervical cancer specimens were identified from women living in the U.S.