Publications by authors named "B Pichon"
Article Synopsis
- This study aimed to understand how hereditary spastic paraplegias (HSP) affect bladder function and symptoms in patients.
- A retrospective review included 122 mostly male patients, revealing that bladder dysfunction typically starts later than motor issues and is linked to specific genetic mutations.
- The findings highlight that detrusor overactivity is common among these patients, indicating bladder issues often arise as mobility worsens.
Designing iron oxide nanoparticles (IONPs) to effectively combine magnetic hyperthermia (MH) and photothermia (PTT) in one IONP formulation presents a significant challenge to ensure a multimodal therapy allowing the adaptation of the treatment to each patient. Recent research has highlighted the influence of factors such as the size, shape, and amount of defects on both therapeutic approaches. In this study, 20-25 nm spherical IONPs with a spinel composition were synthesized by adapting the protocol of the thermal decomposition method to control the amount of defects.
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- Streptococcus mitis is a major contributor to infective endocarditis (IE), but its genetics and disease-causing abilities are not well understood due to the disease's rarity.
- Researchers conducted whole genome sequencing on 129 S. mitis samples from UK bloodstream infections over 15 years, finding a high level of genetic diversity among isolates without a single dominant lineage.
- The study identified a variable presence of virulence genes, suggesting that S. mitis acts as an accidental pathogen in IE cases rather than being driven by specific resistant or aggressive strains.
Within communities, species are wrapped in a set of feedbacks with each other and with their environment. When such feedbacks are strong enough they can generate alternative stable states. So far, research on alternative stable states has mostly focused on systems with a small number of species and a limited diversity of interaction types.
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