Risk Factors for Postoperative Infection in Patients After Pilon Fracture Fixation.

The combination of high energy fractures, extensive soft tissue trauma, and high infection rates in pilon fractures of the distal tibia have long challenged surgeons. Despite the ample evidence, there is no consensus regarding the factors that may influence postoperative infections following surgical management of these fractures. This study aimed to investigate the risk factors for postoperative infections in patients undergoing surgical management for pilon fractures.

Notochord segmentation in zebrafish controlled by iterative mechanical signaling.

In bony fishes, patterning of the vertebral column, or spine, is guided by a metameric blueprint established in the notochord sheath. Notochord segmentation begins days after somitogenesis concludes and can occur in its absence. However, somite patterning defects lead to imprecise notochord segmentation, suggesting that these processes are linked.

COVID-19 Resulted in Reduction Trainee Bedside Experience, But No Reduction in Surgical Experience.

Purpose: Because of the concerns regarding residency process during the pandemic, this study aimed to investigate the volume of clinical interactions of orthopaedic residents at a tertiary hospital by reporting the number of patients treated in the outpatient clinic, inpatient ward, and operating room.

Methods: This retrospective chart study evaluated variables such as volume of clinical interactions of orthopaedic residents at a tertiary hospital by reporting the number of patients treated in the outpatient clinic, inpatient ward, and operating room, from an orthopaedic department in a tertiary trauma center throughout the COVID-19 pandemic era. Comparing these measures was an indirect evaluation tool for measuring the amount of work completed and clinical exposure gained by the residents.

Dynamic BMP signaling mediates notochord segmentation in zebrafish.

The vertebrate spine is a metameric structure composed of alternating vertebral bodies (centra) and intervertebral discs. Recent studies in zebrafish have shown that the epithelial sheath surrounding the notochord differentiates into alternating cartilage-like (col2a1/col9a2+) and mineralizing (entpd5a+) segments which serve as a blueprint for centra formation. This process also defines the trajectories of migrating sclerotomal cells that form the mature vertebral bodies.

Axial segmentation by iterative mechanical signaling.

In bony fishes, formation of the vertebral column, or spine, is guided by a metameric blueprint established in the epithelial sheath of the notochord. Generation of the notochord template begins days after somitogenesis and even occurs in the absence of somite segmentation. However, patterning defects in the somites lead to imprecise notochord segmentation, suggesting these processes are linked.