[Identification of multivessel coronary disease using myocardial Thallium-201 and dipyridamole scintigraphy in acute myocardial infarction in the thrombolytic era].

Recently some Authors observed a low sensitivity of submaximal exercise thallium-201 myocardial scintigraphy for predicting multivessel coronary disease in patients with recent acute myocardial infarction (AMI) treated with thrombolytic therapy. The aim of our study was to evaluate the accuracy of dipyridamole thallium-201 single photon emission computerized tomography (DIP-SPECT) for predicting the location and the extent of coronary artery disease in patients with recent uncomplicated AMI and to compare the results obtained in patients treated with thrombolytic therapy (Group T) to those obtained in patients treated with non-thrombolytic therapy (Group NT). We examined 61 consecutive patients with recent uncomplicated AMI by predischarge DIP-SPECT as well as by coronary angiography.

[Determination of myocardial risk on basis of the outcome of previous myocardial infarcts. Advantages of myocardial tomoscintigraphy using thallium with dipyridamole].

Exercise stress test, 24-hour-ambulatory electrocardiographic monitoring and myocardial perfusion 201-Thallium single photon emission computerized tomography (SPECT) with dipyridamole pharmacological stress probably have different sensitivities and specificities for the identification of residual ischemia after an acute myocardial infarction. Their clinical value is still a matter of debate. To comparatively evaluate various non-invasive methods, we studied 63 patients with previous myocardial infarction consecutively referred to our Nuclear Medicine Department to undergo myocardial dipyridamole (0.

[Importance of late reversibility in the identification of myocardial viability at risk after myocardial infarction].

The prevalence of late reversibility in single photon emission computed tomography (SPECT) thallium 201 stress/redistribution studies is still controversial. The aim of our work was to evaluate the prevalence of late reversibility at infarct site in an unselected population of patients with previous acute myocardial infarction (AMI). We studied by SPECT thallium 201 and pharmacologic stress with dipyridamole (DIP) as well as by two-dimensional echocardiography 58 consecutive patients with previous AMI (50 men of mean age 57 years, range 40-73; 8 women of mean age 58 years, range 50-68).

Myocardial perfusion in Friedreich's ataxia: assessment by dipyridamole thallium-201 imaging.

In order to assess myocardial perfusion in patients with Friedreich's ataxia, we carried out dipyridamole-thallium imaging in 13 cardiologically asymptomatic patients (aged 16 to 39; mean age 24) with various degrees of left ventricular hypertrophy; all showed electrocardiographic ST and/or T wave abnormalities before scintigraphy. After dosing with dipyridamole-201 thallium, we found: a completely reversible perfusion defect in the apical and a partially reversible defect in the posterolateral wall of the left ventricle in 1 case; a partially reversible perfusion defect in the anterior and posterior walls of the left ventricle in 1 case; and a persistent anterolateral perfusion defect in 1 case. The remaining 10 patients showed no scintigraphic abnormalities.