Wavelet transform: A better approach for the evaluation of instantaneous changes in heart rate variability.

The aim of our study was to validate the Vaidyanathan wavelet tool for HRV analysis during orthostatic testing. Two groups of normotensive male subjects were studied: 13 adolescents and 27 young adults. Both groups consisted of subjects with negative, (N-), and with positive family history for hypertension, (N+).

Effect of lesions to the supramammillary area of the posterior hypothalamus on atrial natriuretic peptide release following acute blood volume expansion in conscious Wistar rats.

Acute blood volume expansion (AVE) is a potent stimulus for atrial natriuretic peptide (ANP) release. Since several central nervous structures are well known for their involvement in the regulation of fluid and electrolyte homeostasis and in the secretion of central ANP, we carried our experiments on 33 conscious Wistar rats in order to determine if the integrity of the supramammillary (SMA) hypothalamic area is essential for the peripheral ANP response to AVE. We performed stereotaxic electrolytic lesions of SMA in part of the animals.

Effect of dopamine receptor blockade on the renal excretory response to acute volume expansion (AVE) in conscious Brattleboro rats.

Unlabelled: All the studies were performed on chronically cannulated, conscious Brattleboro rats, housed in metabolic cages under standard conditions. The renal excretory indices: diuresis (V), sodium (UNa.V), potassium (UK.

Renal excretory function, atrial natriuretic peptide (ANP) and plasma renin activity (PRA) during long-term sodium loading in rats.

The effect of chronic sodium loading on the level of plasma atrial natriuretic peptide (ANP) and on plasma renin activity (PRA), as well as on the renal excretory function was studied. Fifty-six standardly bred Long Evans rats were divided into three experimental groups: controls, rats drinking 170 mmol NaCl/l solution instead of water, and rats consuming food with high sodium content (850 mmol NaCl/kg) for 21 days. During the study, we measured the amount of fluid intake, the parameters of the renal function: diuresis (VU); sodium, potassium and cloride excretion (UNa V, UKV and UClV), and the dynamics of body mass.

Potentiation of the diuretic and natriuretic effect of furosemide by the calcium antagonist nifedipine.

The renal excretory function was studied in rats under control conditions, after treatment with nifedipine, with furosemide and combined treatment with nifedipine and furosemide. The experimental animals were investigated in metabolic cages. Spontaneously excreted urine was collected for 6 h (under control conditions and when nifedipine was applied) and for two hours in the experiments with furosemide treatment.